Dual Treatment of Hemichorea-Hemiballismus Syndrome with Tetrabenazine and Chemodenervation

oleh: Chizoba C. Umeh, Paige Nichols, Liana S. Rosenthal, Zoltan Mari

Format: Article
Diterbitkan: Ubiquity Press 2012-10-01

Deskripsi

<p><strong>Background:</strong> Hemichorea&ndash;hemiballismus involves unilateral involuntary flailing movements and random jerking movements involving proximal or distal muscles. We describe a case of hemichorea&ndash;hemiballismus with dystonia after stroke. Treatment with tetrabenazine and chemodenervation produced beneficial responses. Effective treatment of both hemichorea&ndash;hemiballismus and dystonia due to stroke has not been reported.</p> <p><strong>Case Report:</strong> A 65-year-old male developed left hemichorea&ndash;hemiballismus and dystonia after a right hemisphere stroke. He underwent initial treatment with neuroleptics and anticonvulsants without improvement. Subsequent treatment with tetrabenazine improved the hemichorea&ndash;hemiballismus and chemodenervation reduced the dystonia.</p> <p><strong>Discussion:</strong> Hemichorea&ndash;hemiballismus associated with dystonia can be improved with both tetrabenazine and chemodenervation.</p>