Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
oleh: Tim Schneider, Lee-Hsueh Hung, Masood Aziz, Anna Wilmen, Stephanie Thaum, Jacqueline Wagner, Robert Janowski, Simon Müller, Silke Schreiner, Peter Friedhoff, Stefan Hüttelmaier, Dierk Niessing, Michael Sattler, Andreas Schlundt, Albrecht Bindereif
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-05-01 |
Deskripsi
Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protein IMP3.