Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes
oleh: Paul M. H. Tran, Fran Dong, Eileen Kim, Katherine P. Richardson, Lynn K. H. Tran, Kathleen Waugh, Diane Hopkins, Richard D. Cummings, Peng George Wang, Marian J. Rewers, Jin-Xiong She, Sharad Purohit
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
Type I diabetes is characterized by autoantibodies directed against protein or non-protein self-antigens. Here the authors profile glycan reactive anti-carbohydrate antibodies (ACA) in a longitudinal and cross-sectional childhood diabetes cohort and associate clusters of ACA with disease progression.