A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I

oleh: Marius Schulte, Klaudia Frick, Emmanuel Gnandt, Sascha Jurkovic, Sabrina Burschel, Ramona Labatzke, Karoline Aierstock, Dennis Fiegen, Daniel Wohlwend, Stefan Gerhardt, Oliver Einsle, Thorsten Friedrich

Format: Article
Diterbitkan: Nature Portfolio 2019-06-01

Deskripsi

Respiratory complex I plays a central role in cellular energy metabolism coupling NADH oxidation to proton translocation. Here, the authors report the structure of the electron input part of Aquifex aeolicus complex I at up to 1.8 Å resolution with bound substrates in the reduced and oxidized states.