Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs
oleh: Shawn M. Lyons, Dorota Gudanis, Steven M. Coyne, Zofia Gdaniec, Pavel Ivanov
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-10-01 |
Deskripsi
RNA G-quadruplexes (RG4) occur in vivo and have regulatory roles in mRNA metabolism. Here the authors show that the guanine residue stretches at the 5’ end of tRNA-derived stress-induced RNAs mediate the formation of tetramolecular RG4 structures, which play a role in the post-transcriptional regulation of gene expression.