Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy
oleh: Chunbai He, Xiaopin Duan, Nining Guo, Christina Chan, Christopher Poon, Ralph R. Weichselbaum, Wenbin Lin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
Blockade of PD-L1 is usually not very effective in colon cancer patients. Here, the authors show the efficacy of PD-L1 blockade in combination with coordination polymer nanoparticles carrying oxaliplatin and a photosensitizer to induce anti-tumor immunity in metastatic models of colon cancer.