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The present study addresses the three-dimensional flow and nonlinear radiative heat transfer of an Oldroyd-B nanofluid flow over a stretching surface with the addition effects of uniform heat source/sink and convective boundary conditions. Suitable similarity transformations are employed to reduce the governing partial differential equations into coupled nonlinear ordinary differential equations. These nonlinear ordinary differential equations are then solved numerically by RKF-45 method. The effects of physical parameters on velocity, temperature and concentration profiles are investigated and discussed. The result reveals that the nonlinear radiation is more effective than that of linear radiation. Keywords: Oldroyd-B fluid, Nanoparticles, Nonlinear thermal radiation, Convective boundary conditions, Uniform heat source/sink