Noninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis

oleh: Yulin Sun, Zhengguang Guo, Xiaoyan Liu, Lijun Yang, Zongpan Jing, Meng Cai, Zhaoxu Zheng, Chen Shao, Yefan Zhang, Haidan Sun, Li Wang, Minjie Wang, Jun Li, Lusong Tian, Yue Han, Shuangmei Zou, Jiajia Gao, Yan Zhao, Peng Nan, Xiufeng Xie, Fang Liu, Lanping Zhou, Wei Sun, Xiaohang Zhao

Format: Article
Diterbitkan: Nature Portfolio 2022-05-01

Deskripsi

More sensitive and specific non-invasive biomarkers are desired for early detection of cancer. Here, the authors show a protein signature in the urine that increases sensitivity for colorectal cancer detection when combined with fecal immunochemical tests and corrects diagnosis in some fecal immunochemical tests-negative patients.