An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing

oleh: Kean Hean Ooi, Mengying Mandy Liu, Jie Wen Douglas Tay, Seok Yee Teo, Pornchai Kaewsapsak, Shengyang Jin, Chun Kiat Lee, Jingwen Hou, Sebastian Maurer-Stroh, Weisi Lin, Benedict Yan, Gabriel Yan, Yong-Gui Gao, Meng How Tan

Format: Article
Diterbitkan: Nature Portfolio 2021-03-01

Deskripsi

As the COVID-19 pandemic continues, variants of the virus are emerging. Here the authors present a diagnostic assay that can detect wildtype and known variants using engineered Cas12a.