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Hypoxia is common in C.V stroke patients and monitoring of SpO2 by pulse oximetry should be done in the acute phase. Many a time, it is felt that physical changes on the affected side or i.v infusions may alter oximeter readings. Thirty patients 18 men (60%) 12 women (40%) : 19 left hempiaresis (63.3%) were recruited. The maximum differences between simultaneous left and right arm readings was 1% SpO2. Heart rate fluctuated more but no affected/non-affected side pattern was seen. Mean SPO2 was 95% on both sides. Mean HR was 82 bpm on both sides. There was no significant difference between the two sides for either parameter.