Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
oleh: Jianhua Zhang, Ran Tao, Katherine F. Campbell, Juliana L. Carvalho, Edward C. Ruiz, Gina C. Kim, Eric G. Schmuck, Amish N. Raval, André Monteiro da Rocha, Todd J. Herron, José Jalife, James A. Thomson, Timothy J. Kamp
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-05-01 |
Deskripsi
Cardiac fibroblasts (CFs) play critical roles in heart development, homeostasis, and disease. Here the authors efficiently differentiate human pluripotent stem cells through second heart field progenitors to CFs that exhibit features and functional properties similar to native CFs.