Opposing functions of the Hda1 complex and histone H2B mono-ubiquitylation in regulating cryptic transcription in <i>Saccharomyces cerevisiae</i>
oleh: Margaret K Shirra, Rachel A Kocik, Mitchell A Ellison, Karen M Arndt
| Format: | Article |
|---|---|
| Diterbitkan: | Oxford University Press 2021-08-01 |
Deskripsi
AbstractMaintenance of chromatin structure under the disruptive force of transcription requires cooperation among numerous regulatory factors. Histone post-translational modifications can regulate nucleosome stability and influence the disassembly and reassembly of nucleosomes during transcription elongation. The Paf1 transcription elongation complex, Paf1C, is required for several transcription-coupled histone modifications, including the mono-ubiquitylation of H2B. In Saccharomyces cerevisiaeFLO8HDA3rtf1rtf1