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Anionic phospholipids control mechanisms of GPCR-G protein recognition
oleh: Naveen Thakur, Arka P. Ray, Liam Sharp, Beining Jin, Alexander Duong, Niloofar Gopal Pour, Samuel Obeng, Anuradha V. Wijesekara, Zhan-Guo Gao, Christopher R. McCurdy, Kenneth A. Jacobson, Edward Lyman, Matthew T. Eddy
Format: | Article |
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Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
In cell membranes, lipids are ubiquitous regulators of protein function. Here, Thakur et al. observe anionic phospholipids impact the conformational dynamics of a class A human GPCR.