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Glioblastoma multiforme (GBM) is a high-grade tumor of the brain that arises from the supporting cells of neurons (astrocytes and oligodendrocytes) within the brain. GBM is a rare occurrence in children but fatal; hence, timely diagnosis is crucial to the prognosis of the patients. While GBM can present with several signs and symptoms, headaches and vomiting and headaches relieved by vomiting are common presenting complaints. Strabismus is an uncommon sign of GBM. Here, we discuss an 18-year-old girl diagnosed with GBM who presented with strabismus and was initially misdiagnosed as a squint and revise some of the literature already present on Glioblastoma multiforme.