Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Myasthenia Gravis and Large Granular Lymphocytic Leukemia: a rare association
oleh: Yumeng Zhang, MD, Christa Varnadoe, BS, Ankita Tandon, DO, Peter Forsyth, MD, Rami Komrokji, MD, Lubomir Sokol, MD
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2020-01-01 |
Deskripsi
Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder sometimes observed in hematologic malignancies as a paraneoplastic syndrome. T-cell Large Granular Lymphocytic Leukemia (T-LGLL) is a rare lymphoproliferative clonal frequently associated with autoimmune disorders. Here we report two patients with T-LGLL who developed MG. In both patients the MG was bulbar without generalized weakness and did not involve the thymus. The treatment of T-LGLL led to the resolution of MG symptoms and decrease in acetylcholine receptor antibody titers in both patients suggesting a causative association.