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PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex
由: Liangguang Lin, Congcong Zhang, Yongwu Chen, Yi Wang, Dinghe Wang, Xiaolei Liu, Muyang Wang, Juan Mao, Jianjun Zhang, Weiman Xing, Linchuan Liu, Jianming Li
格式: | Article |
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出版: | Nature Portfolio 2019-08-01 |
实物特征
Endoplasmic reticulum (ER)-associated degradation (ERAD) removes misfolded proteins from the secretory pathway. Here the authors identify two plant-specific proteins in Arabidopsis, PAWH1 and PAWH2, that bind to and stabilise the ER-anchored ubiquitin ligase Hrd1.