Sub-nanowatt resolution direct calorimetry for probing real-time metabolic activity of individual C. elegans worms

oleh: Sunghoon Hur, Rohith Mittapally, Swathi Yadlapalli, Pramod Reddy, Edgar Meyhofer

Format: Article
Diterbitkan: Nature Portfolio 2020-06-01

Deskripsi

Calorimetry is widely used for metabolic studies, but measurements of single cells and small organisms are limited by the sensitivity of current techniques. Here the authors develop a sensitive platform for performing time-resolved metabolic measurements of single C. elegans worms from larval to adult stages.