Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry
oleh: Sofani Tafesse Gebreyesus, Asad Ali Siyal, Reta Birhanu Kitata, Eric Sheng-Wen Chen, Bayarmaa Enkhbayar, Takashi Angata, Kuo-I Lin, Yu-Ju Chen, Hsiung-Lin Tu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
Single-cell proteomics is an emerging approach to characterize cell-to-cell differences. Here, the authors develop chips that enable complete proteomic sample processing down to the single-cell level and integrate them with DIA-MS into a streamlined single-cell proteomics workflow.