Strategies for the prevention and treatment of endometrial injury

oleh: LI Jiaming, YANG Chao, MA Li

Format: Article
Diterbitkan: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-09-01

Deskripsi

Endometrial injury is the main fact leading to the damage of endometrial basal layer. It is usually caused by traumatic treatment, inflammatory injury, radiation, chemical drug-related injury, and delivery-related diverticulum. The use of hyaluronic acid, decellularized matrix, amniotic membrane, platelet-rich plasma, mesenchymal stem cells (especially scaffold-based therapeutic delivery) has been proved to reduce post-injury scar formation and promote endometrial growth and repair, which provides a new therapeutic strategy for repairing the damaged endometrium with improved tolerability and fertility outcomes.