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An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells
oleh: Y. Bill Kim, Kevin T. Zhao, David B. Thompson, David R. Liu
Format: | Article |
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Diterbitkan: | Nature Portfolio 2019-07-01 |
Deskripsi
Inefficient delivery of proteins into mammalian cells limits their use in research and therapy. Here, the authors discover that ProTα, a small, intrinsically disordered human protein can facilitate efficient cationic lipid-mediated protein delivery of genome editing proteins into mammalian cells.