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<p>Gap junctions (GJ) is an important way to transmit signals among body cells. Studies have confirmed that changes on structure and composition of gap junction proteins are associated with many kinds of diseases. Movement disorders is a common disease of the central nervous system (CNS), which has a certain degree of correlation with GJ, and it has become a key factor in the domestic and foreign research of pathogenesis and treatment mechanism of central nervons system diseases. This paper reviews GJ and its relationship with movement disorders.</p><p> </p><strong>DOI: </strong>10.3969/j.issn.1672-6731.2016.12.011