Hereditary persistence of fetal hemoglobin
oleh: Dharmesh Chandra Sharma, Sachin Singhal, Poonam Woike, Sunita Rai, Mahesh Yadav, Rajesh Gaur
| Format: | Article |
|---|---|
| Diterbitkan: | Wolters Kluwer Medknow Publications 2020-01-01 |
Deskripsi
Hereditary persistence of fetal hemoglobin (HPFH) is a benign condition in which significant fetal hemoglobin production continues well into adulthood, disregarding the normal shutoff point after which only adult-type hemoglobin should be produced. The percentage of incorrect expression might be as low as 10%–15% or as high as 100% of the total hemoglobin, usually higher in homozygotes than in heterozygotes. The present case is a typical example of homozygous HPFH.