Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)

oleh: Ivana Jukic, Dorotea Bozic, Milos Lalovac, Mirela Pavicic Ivelja, Mislav Radic, Zeljko Sundov, Jonatan Vukovic

Format: Article
Diterbitkan: Karger Publishers 2022-05-01

Deskripsi

Coronavirus disease-2019 (COVID-19) has become associated with prothrombotic state that could lead to severe arterial thrombotic complications. In the case of severe COVID-19 infection, hepatic dysfunction has been observed in more than 50% of patients. In this article, we present a case of aortic thrombosis associated with COVID-19 infection and methylenetetrahydrofolate reductase gene polymorphism (C677T) treated with rivaroxaban resulting in acute liver failure with fatal outcome.