Establishment of SIAISi018-A, an induced pluripotent stem cell (iPSC) line from a healthy 45-year-old Chinese Han

oleh: Yi Zhang, Jiajun Shou, Wentao Gu, Weihao Di, Jian Zhao, Ying Wang, Shixin Gu

Format: Article
Diterbitkan: Elsevier 2022-04-01

Deskripsi

A 45-year-old Han Male from China contributed peripheral blood mononuclear cells induced by reprogramming human OKSM transcription factors (OCT3/4, KLF4 SOX2 and C-MYC) with a non-integrated additional vector system. Immunological markers confirmed the pluripotent nature of IPSC. Spontaneous tridermal differentiation confirmed the differentiation ability of IPSC with normal karyotype.