Cocaine’s cerebrovascular vasoconstriction is associated with astrocytic Ca2+ increase in mice

oleh: Yanzuo Liu, Yueming Hua, Kicheon Park, Nora D. Volkow, Yingtian Pan, Congwu Du

Format: Article
Diterbitkan: Nature Portfolio 2022-09-01

Deskripsi

Multimodal imaging of the mouse brain following acute cocaine application revealed that cocaine caused a biphasic calcium response in neurons, but not astrocytes, suggesting that these cells play different roles in mediating neurovascular coupling to cocaine.