Structural rearrangements allow nucleic acid discrimination by type I-D Cascade
oleh: Evan A. Schwartz, Tess M. McBride, Jack P. K. Bravo, Daniel Wrapp, Peter C. Fineran, Robert D. Fagerlund, David W. Taylor
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
I-D CRISPR-Cascade can target both single-stranded and double-stranded nucleic acids. Here, Schwartz et. al determine these structures and reveal large-scale rearrangements that allow for target discrimination and destruction.