Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
oleh: Guillaume F. Combes, Hussein Fakhouri, Christophe Moulin, Marion Girod, Franck Bertorelle, Srestha Basu, Romain Ladouce, Martina Perić Bakulić, Željka Sanader Maršić, Isabelle Russier-Antoine, Pierre-François Brevet, Philippe Dugourd, Anita Krisko, Katarina Trajković, Miroslav Radman, Vlasta Bonačić-Koutecký, Rodolphe Antoine
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.