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Infection with <i>Echinococcus</i> spp. causes fibrosis in various vital organs, including the liver and lungs. Hepatic fibrosis is a pathological feature of <i>Echinococcus</i> infection that destroys normal liver tissue, leading to jaundice, cholecystitis, portal hypertension, etc. Severe <i>Echinococcus multilocularis</i> infections lead to liver failure and hepatic encephalopathy. The formation of peripheral fiberboards around the metacestode is a major reason as to why antiparasitic drugs fail to be effectively transported to the lesion site. Studies on the mechanism of hepatic fibrosis caused by <i>Echinococcus</i> are important for treatment in patients. Recent studies have focused on miRNA and TGF-&#946;. More recent findings have focused on the generation of collagen fibers around the metacestode. In this review paper we focus on the mechanism by which the <i>Echinococcus</i> parasite induces fibrosis in liver and some other organs in intermediate hosts&#8212;animals as well as human beings.