Highly hydrated paramagnetic amorphous calcium carbonate nanoclusters as an MRI contrast agent
oleh: Liang Dong, Yun-Jun Xu, Cong Sui, Yang Zhao, Li-Bo Mao, Denis Gebauer, Rose Rosenberg, Jonathan Avaro, Ya-Dong Wu, Huai-Ling Gao, Zhao Pan, Hui-Qin Wen, Xu Yan, Fei Li, Yang Lu, Helmut Cölfen, Shu-Hong Yu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-08-01 |
Deskripsi
Sensitive, biocompatible and stable contrast agents for MRI are in demand. Here, the authors combine gadolinium ions with amorphous calcium carbonate to make stable paramagnetic amorphous carbonate nanoclusters with high MRI contrast and significantly improved biocompatibility over commercial gadolinium-based agents.