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Since May 2022, monkeypox has been gradually spreading across countries. In past reports and treatment consensus, monkeypox is most widely known for its characteristic skin lesions, which are hard, spherical rashes that appear as herpes and pustules and are widely distributed centrifugally over all parts of the body. Prior to the appearance of the rash, carriers of monkeypox are likely to spread the virus to more susceptible people. Attention to the early atypical mucosal manifestations of monkeypox allows for early identification of potential cases of monkeypox, thereby controlling the further spread of the epidemic.