Repurposing Riociguat for Treatment of Refractory Angina Resulting From Coronary Spasm
gan: Valeria MartÃnez Pereyra, MS, Andreas Seitz, MD, Astrid Hubert, PhD, Sascha Beck, MS, Ute Hofmann, PhD, Matthias Schwab, MD, Raffi Bekeredjian, MD, Udo Sechtem, MD, Peter Ong, MD
| Fformat: | Article |
|---|---|
| Cyhoeddwyd: | Elsevier 2021-03-01 |
Disgrifiad
Coronary spasm is a frequent cause of angina despite unobstructed coronary arteries, and symptom control with recommended drugs is limited. We report the case of a 77-year-old woman who had refractory angina despite conventional antianginal treatment. Repurposing riociguat, a soluble guanylate cyclase stimulator, resulted in improvement of symptoms and prevention of spasm. (Level of Difficulty: Intermediate.)