Methyl (R)-2-(2-chlorophenyl)-2-(3-nitrophenylsulfonyloxy)acetate
oleh: Ying-Hua Li, Hong-Wu Xu, Liu-Xue Zhang
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2012-06-01 |
Deskripsi
The reaction between methyl (R)-2-(2-chlorophenyl)-2-hydroxyacetate and 3-nitrobenzenesulfonyl chloride gave the title compound, C15H12ClNO7S, which is a promising intermediate for the synthesis of Clopidrogel, an antiplatelet drug used in the prevention of strokes and heart attacks. In the crystal, molecules are linked through C—H...O interactions, and there is also a short Cl...O contact present [Cl...O = 3.018 (2) Å].