Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis

oleh: Maria Fankhaenel, Farahnaz S. Golestan Hashemi, Larissa Mourao, Emily Lucas, Manal M. Hosawi, Paul Skipp, Xavier Morin, Colinda L.G.J. Scheele, Salah Elias

Format: Article
Diterbitkan: Nature Portfolio 2023-01-01

Deskripsi

Regulation of oriented cell divisions during development is important to position daughter cells and build a structured and functional tissue. Here the authors show that Annexin A1 is a key polarity protein that regulates planar orientation of the cell division axis to guide mammary epithelial morphogenesis.