Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics
oleh: Zhen Chen, Caoqi Lei, Chao Wang, Nan Li, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Jong Min Choi, Sung Yun Jung, Jun Qin, Junjie Chen
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-01-01 |
Deskripsi
AMPK is regulates cellular energy and has been extensively studied, although our knowledge of downstream substrates is incomplete. Here, Chen et al. perform global quantitative analysis for AMPK-dependent sites and validate one hit, ARMC10, as a direct AMPK effector of mitochondrial dynamics.