Find in Library

Understanding the association between food composition and intestinal microbiota in the context of individual health is a critical problem in personalized nutrition. The objective of the present research was to elucidate the influence of <i>Lactiplantibacillus plantarum</i> ST-III and fructooligosaccharides (FOS) on the intestinal microbiota structure. We found that <i>L</i><i>. plantarum</i> ST-III and FOS interventions remarkably enhanced the levels of cecal short-chain fatty acids (SCFAs), especially acetic, butyric, and valeric acids. Moreover, <i>L. plantarum</i> ST-III and/or FOS intervention obviously altered the intestinal microbiota structure. At the genus level, <i>L. plantarum</i> ST-III and/or FOS intervention remarkably elevated the proportion of <i>Sutterella</i>, <i>Pediococcus</i>, <i>Proteus</i>, <i>Parabacteroides</i>, <i>Prevotella</i> and <i>Desulfovibrio</i>. Correlation analysis further uncovered that the specific compositional features of intestinal microbiota were strongly related to the concentration of cecal SCFAs. Our results offered scientific evidence to understanding the association between food composition and intestinal microbiota.