Evaluation of short and mid-term clinical outcomes in patients with aortic coarctation treated with self-expandable stents

oleh: Mahmoud Mohammadzadeh Shabestari, Ali Eshraghi, Farnaz Hakim Attar, Fereshteh Ghaderi, Hoorak Poorzand, Amir Hossein Mohammadzadeh Shabestari, Behzad Alizadeh, Negar Morovatdar, Bahram Shahri, Hedieh Alimi, Mohammad Tayyebi, Arash Gholoobi, Vahid Reza Askari, Yousef Ali Garivani, Mohammad Mohammadzadeh Shabestari, Vafa Baradaran Rahimi

Format: Article
Diterbitkan: Nature Portfolio 2024-05-01

Deskripsi

Abstract The present study aimed to evaluate the outcomes of percutaneous treatment of aortic coarctation using self-expandable uncovered Nitinol stents. We conducted a retrospective clinical data review of all patients with aortic coarctation and treated with self-expandable uncovered Nitinol stents at our institution between 2009 and 2019. The gradient pressure across the coarctation site was measured using aortography. Follow-up echocardiography and computed tomography angiography were performed to assess possible stent complications. A total of 127 stents were successfully implanted in 125 patients (64.8% males) with a mean age of 35.36 ± 11.9 years. The gradient across the coarctation site decreased significantly from 67.48 ± 14.79 to 5.04 ± 3.01 mmHg (P < 0.001) after self-expandable stent implantation. Systolic blood pressure (SBP) decreased significantly from 175.53 ± 15.99 to 147.22 ± 12.83 mmHg (P < 0.001) after self-expandable stenting. There were no major technical or clinical complications, including balloon rupture, aneurysmal formation, infection, secondary stent migration, thrombosis, death during the procedure, and in-hospital mortality. On a mean follow-up of 48 ± 23.6 months (12–120 months), the gradient [from 59.43 ± 15.42 to 3.72 ± 1.38 mmHg (P < 0.001)] and SBP [from 175.53 ± 15.99 to 127.99 ± 7.82 mmHg (P < 0.001)] decreased significantly. There was no mortality, aneurysmal formation in the stent site, dislocation, or aortic re-stenosis requiring intervention during mid-term follow-up. Treatment of aortic coarctation using a self-expandable uncovered nitinol stent is safe and effective with promising mid-term outcomes.