Direct Whole-Genome Sequencing of Cutaneous Strains of Haemophilus ducreyi

oleh: Michael Marks, Maria Fookes, Josef Wagner, Rosanna Ghinai, Oliver Sokana, Yaw-Adu Sarkodie, Anthony W. Solomon, David C.W. Mabey, Nicholas R. Thomson

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2018-04-01

Deskripsi

Haemophilus ducreyi, which causes chancroid, has emerged as a cause of pediatric skin disease. Isolation of H. ducreyi in low-income settings is challenging, limiting phylogenetic investigation. Next-generation sequencing demonstrates that cutaneous strains arise from class I and II H. ducreyi clades and that class II may represent a distinct subspecies.