Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation
oleh: Elena Ortiz-Zapater, Dustin C. Bagley, Virginia Llopis Hernandez, Luke B. Roberts, Thomas J. A. Maguire, Felizia Voss, Philipp Mertins, Marieluise Kirchner, Isabel Peset-Martin, Grzegorz Woszczek, Jody Rosenblatt, Michael Gotthardt, George Santis, Maddy Parsons
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
The epithelial protein Coxsackievirus Adenovirus Receptor (CAR) is a virus receptor but may have other functions. Here the authors show that deletion of CAR in mice leads to reduced house dust mite-induced lung inflammation, reduced neutrophil accumulation and alterations in airway remodelling.