An insight into genetics of non-syndromic cleft palate
oleh: Nayereh Nouri, Padideh Karimi, Salehi Mansoor, Mehrdad Memarzadeh, Hamid Ganji, Maryam Sedghi
| Format: | Article |
|---|---|
| Diterbitkan: | Wolters Kluwer Medknow Publications 2013-01-01 |
Deskripsi
Our proband is a 29-year-old man, who is affected with soft cleft palate and hypernasality. A study of about six generations of this family pedigree shows that cleft palate has repeatedly occurred in males, with probably a X-linked recessive pattern of inheritance. Interestingly, the sister of the proband is affected with hypernasality and she has an affected son. This is the first report of X-linked inheritance pattern of cleft palate in Iran.