TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
oleh: Hao Yan, Chuan Chen, Huicheng Chen, Hui Hong, Yan Huang, Kun Ling, Jinghua Hu, Qing Wei
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-05-01 |
Deskripsi
Most cells possess sensory cilia, which need to be gated properly. Here the authors show that the C. elegans proteins TALP-3 and ANKR-26 coordinate cilia gating in the context of transition fibers and that this mechanism is conserved in mammalian cells and likely implicated in certain ciliopathies.