Whole blood DNA methylation analysis reveals respiratory environmental traits involved in COVID-19 severity following SARS-CoV-2 infection

oleh: Guillermo Barturen, Elena Carnero-Montoro, Manuel Martínez-Bueno, Silvia Rojo-Rello, Beatriz Sobrino, Óscar Porras-Perales, Clara Alcántara-Domínguez, David Bernardo, Marta E. Alarcón-Riquelme

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Genetic associations with severe COVID-19 have been discovered, but epigenetic associations are not as well described. Here, the authors perform a genome-wide epigenetic analysis of COVID-19 patients, discovering an interaction between environmental exposure, genetics, and epigenetics which might play a role in severe disease.