Mapping the sensing spots of aerolysin for single oligonucleotides analysis

oleh: Chan Cao, Meng-Yin Li, Nuria Cirauqui, Ya-Qian Wang, Matteo Dal Peraro, He Tian, Yi-Tao Long

Format: Article
Diterbitkan: Nature Portfolio 2018-07-01

Deskripsi

Nanopores are an emerging powerful single-molecule method of DNA sequencing. Here the authors map the structure of aerolysin for use as a nanopore and show detection of modified and unmodified nucleobases.