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Mapping the sensing spots of aerolysin for single oligonucleotides analysis
oleh: Chan Cao, Meng-Yin Li, Nuria Cirauqui, Ya-Qian Wang, Matteo Dal Peraro, He Tian, Yi-Tao Long
Format: | Article |
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Diterbitkan: | Nature Portfolio 2018-07-01 |
Deskripsi
Nanopores are an emerging powerful single-molecule method of DNA sequencing. Here the authors map the structure of aerolysin for use as a nanopore and show detection of modified and unmodified nucleobases.