Description of a possible clonal expansion of Plasmodium vivax in Manaus - Amazonas - Brazil

oleh: Maria das Graças Costa Alecrim, Wilson Duarte Alecrim, Vanize Macêdo, Caroline T. Korves, Donald R. Roberts, Jun Li, Margery Sullivan, Thomas F. McCutchan

Format: Article
Diterbitkan: Sociedade Brasileira de Medicina Tropical (SBMT) 1999-06-01

Deskripsi

Atypical P. vivax cases reported in Manaus municipality led us to detect a genetic isolate of P. vivax. Variable regions of SSUrRNA were examined from the initial time of infection and in the two recrudescences/relapses from a patient exhibiting chloroquine and primaquine resistance. A unique isolate, found at all stages of infection, suggests the presence of a clonal expansion.