LMO7 deficiency reveals the significance of the cuticular plate for hearing function
oleh: Ting-Ting Du, James B. Dewey, Elizabeth L. Wagner, Runjia Cui, Jinho Heo, Jeong-Jin Park, Shimon P. Francis, Edward Perez-Reyes, Stacey J. Guillot, Nicholas E. Sherman, Wenhao Xu, John S Oghalai, Bechara Kachar, Jung-Bum Shin
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2019-03-01 |
Deskripsi
In contrast to the extensively studied mechanosensory hair bundle, the cuticular plate is not as well understood. In this study, authors describe the discovery of a hair cell protein called LIM only protein 7, which is localized in the cuticular plate and the cell junction and may play a role in age-related deafness.