Insertion of ammonia into alkenes to build aromatic N-heterocycles

oleh: Shuai Liu, Xu Cheng

Format: Article
Diterbitkan: Nature Portfolio 2022-01-01

Deskripsi

Aromatic heterocycles containing nitrogen are ubiquitous in biologically relevant small molecules. Here the authors show an unorthodox methodology for their synthesis, by inserting the nitrogen atom into a carbon ring, with ammonia in electrochemical conditions.