Single-cell mutation identification via phylogenetic inference
oleh: Jochen Singer, Jack Kuipers, Katharina Jahn, Niko Beerenwinkel
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-12-01 |
Deskripsi
Cross-cell heterogeneity of genotypes can be revealed by analyzing single-cell sequencing data. Here the authors develop a tool for single-cell variant calling via phylogenetic inference, and use it to analyze cancer genomics datasets.