Balancing a genetic toggle switch by real-time feedback control and periodic forcing

oleh: Jean-Baptiste Lugagne, Sebastián Sosa Carrillo, Melanie Kirch, Agnes Köhler, Gregory Batt, Pascal Hersen

Format: Article
Diterbitkan: Nature Portfolio 2017-11-01

Deskripsi

Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit near its unstable state.