Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine

oleh: Erin S. Calipari, Arthur Godino, Emily G. Peck, Marine Salery, Nicholas L. Mervosh, Joseph A. Landry, Scott J. Russo, Yasmin L. Hurd, Eric J. Nestler, Drew D. Kiraly

Format: Article
Diterbitkan: Nature Portfolio 2018-01-01

Deskripsi

Cocaine addiction is accompanied by dysfunction in neural circuits related to reward, but it is unclear how these adaptations occur. Here, authors identify granulocyte-colony stimulating factor as a potent mediator of cocaine-induced adaptations, and show that it can alter the motivation for cocaine.