Insights from the reanalysis of high-throughput chemical genomics data for <i>Escherichia coli</i> K-12

oleh: Peter I-Fan Wu, Curtis Ross, Deborah A Siegele, James C Hu

Format: Article
Diterbitkan: Oxford University Press 2021-01-01

Deskripsi

AbstractDespite the demonstrated success of genome-wide genetic screens and chemical genomics studies at predicting functions for genes of unknown function or predicting new functions for well-characterized genes, their potential to provide insights into gene function has not been fully explored. We systematically reanalyzed a published high-throughput phenotypic dataset for the model Gram-negative bacterium Escherichia coli