A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

oleh: Griffin M. Schroeder, Chapin E. Cavender, Maya E. Blau, Jermaine L. Jenkins, David H. Mathews, Joseph E. Wedekind

Format: Article
Diterbitkan: Nature Portfolio 2022-01-01

Deskripsi

Riboswitches contain an aptamer domain that recognizes a metabolite and an expression platform that regulates gene expression. Here the authors report the crystal structure of a preQ1-sensing riboswitch from Carnobacterium antarcticus that shows two metabolites in a single binding pocket.